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T10885 |
CRAC intermediate 2
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Others
,
Calcium Channel
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CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis. |
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T10884 |
CRAC intermediate 1
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5-(S)-Fluorowillardiine |
Calcium Channel
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CRAC intermediate 1 (5-(S)-Fluorowillardiine) is a key intermediate in the chemical synthesis of a series of CRAC channel inhibitors. |
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T13047 |
Synta66
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Calcium Channel
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Synta66 is a store-operated calcium entry channel Orai inhibitor, and used for the research of neurological disease. |
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T24984 |
5J-4
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Calcium Channel
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5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE). 5J-4 reduces the production of IL-17 and decreases the expression of RORα and RORγt. |
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T3651 |
YM-58483
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YM 58483,BTP2 |
Calcium Channel
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YM-58483 (BTP2) is a specific and effective inhibitor of CRAC channels and subsequent Ca2+ signals. |
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T2170 |
SKF-96365 hydrochloride
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SKF96365 |
Apoptosis
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Potassium Channel
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Calcium Channel
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TRP/TRPV Channel
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Autophagy
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SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells. SKF-96365 hydrochloride can induce cytoprotective autopha... |
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T8867 |
RO2959 Hydrochloride
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RO2959 HCl |
IL Receptor
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Calcium Channel
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Interleukin
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RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2. |
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TQ0033 |
Zegocractin
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CM-4620,N-(5-(6-Chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)pyrazin-2-yl)-2-fluoro-6-methylbenzamide,CM4620 |
Calcium Channel
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Zegocractin (CM-4620) is a calcium-release activated calcium-channel (CRAC channel) inhibitor. |
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T15423 |
GSK-7975A
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Calcium Channel
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GSK-7975A is a potent and orally available inhibitor of CRAC channel. |
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T16688 |
Pyr6
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N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide |
TRP/TRPV Channel
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Pyr6 (N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide) is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influx inhibition in thapsigargin depleted native RBL-2H3 cells).Pyr6 ... |
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T24112 |
GSK-5503A
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GSK5503A |
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GSK-5503A is a novel channel blocker of CRAC. |
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T61677 |
PiCRAC-1
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piCRAC-1 is a powerful inhibitor of the photoinducible Ca2+ release-activated Ca2+ (CRAC) channel. It effectively alleviates thrombocytopenia and hemorrhage [1]. |
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T68408 |
AMG-1
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AMG-1 is a specific CRAC channel inhibitor. AMG-1 blocks the function of effector T cells, but not regulatory T cells in vitro and it attenuates the progression and severity of EAE in vivo. |
